Use of Computational Biochemistry for Elucidating Molecular Mechanisms of Nitric Oxide Synthase
Nitric oxide (NO) is an essential signaling molecule in the regulation of multiple cellular processes.It is endogenously synthesized by NO synthase (NOS) as the product of Dog Charms L-arginine oxidation to L-citrulline, requiring NADPH, molecular oxygen, and a pterin cofactor.Two NOS isoforms are constitutively present in cells, nNOS and eNOS, and